A team of government-funded researchers yesterday announced the results of a new study of people with type 2 diabetes that might contradict some long-established standards for controlling blood glucose levels for type 2 patients.
According to the study, funded by the National Heart, Lung, and Blood Institute, intensive insulin therapy to a goal of HbA1c of 6.4% or less actually increased the risk of cardiovascular incidents for a specific segment of people with type 2 diabetes.
The study involved 10,000 patients aged 40-79 with type 2 diabetes, all of whom were already known to be at high risk for cardiovascular disease.
Scientists found the results of the study surprising, given the significant data of previous long-term trials such as UKPDS (performed in type 2) and the DCCT trial (performed in type 1), and others that demonstrated lower A1c levels were associated with significant benefits in lowering the risk of complications from diabetes.
Researchers in the field are working to further evaluate the study's data to determine its impact on the type 2 population at high risk for cardiovascular disease. It is important to note that the study did not involve any patients with type 1 diabetes, involved drug protocols specific to type 2 diabetics, and only involved patients at high risk for cardiovascular disease.
People with type 1 diabetes should continue to follow the advice of their doctors and diabetes care team regarding glucose control.
According to the study, funded by the National Heart, Lung, and Blood Institute, intensive insulin therapy to a goal of HbA1c of 6.4% or less actually increased the risk of cardiovascular incidents for a specific segment of people with type 2 diabetes.
The study involved 10,000 patients aged 40-79 with type 2 diabetes, all of whom were already known to be at high risk for cardiovascular disease.
Scientists found the results of the study surprising, given the significant data of previous long-term trials such as UKPDS (performed in type 2) and the DCCT trial (performed in type 1), and others that demonstrated lower A1c levels were associated with significant benefits in lowering the risk of complications from diabetes.
Researchers in the field are working to further evaluate the study's data to determine its impact on the type 2 population at high risk for cardiovascular disease. It is important to note that the study did not involve any patients with type 1 diabetes, involved drug protocols specific to type 2 diabetics, and only involved patients at high risk for cardiovascular disease.
People with type 1 diabetes should continue to follow the advice of their doctors and diabetes care team regarding glucose control.
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